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Tropomyosin Tpm3.1 Is Required to Maintain the Structure and Function of the Axon Initial Segment
The axon initial segment (AIS) is the site of action potential initiation and serves as a cargo transport filter and diffusion barrier that helps maintain neuronal polarity. The AIS actin cytoskeleton comprises actin patches and periodic sub-membranous actin rings. We demonstrate that tropomyosin is...
Autores principales: | , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7186529/ https://www.ncbi.nlm.nih.gov/pubmed/32344377 http://dx.doi.org/10.1016/j.isci.2020.101053 |