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Nwd1 Regulates Neuronal Differentiation and Migration through Purinosome Formation in the Developing Cerebral Cortex

Engagement of neural stem/progenitor cells (NSPCs) into proper neuronal differentiation requires the spatiotemporally regulated generation of metabolites. Purines are essential building blocks for many signaling molecules. Enzymes that catalyze de novo purine synthesis are assembled as a huge multie...

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Detalles Bibliográficos
Autores principales: Yamada, Seiya, Sato, Ayaka, Sakakibara, Shin-ichi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7186558/
https://www.ncbi.nlm.nih.gov/pubmed/32344379
http://dx.doi.org/10.1016/j.isci.2020.101058