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Circular RNA circNRIP1 Sponges microRNA-138-5p to Maintain Hypoxia-Induced Resistance to 5-Fluorouracil Through HIF-1α-Dependent Glucose Metabolism in Gastric Carcinoma

BACKGROUND: Hypoxia-induced chemoresistance is recognized as a major obstacle to the successful treatment of gastric cancer (GC). Circular RNAs (circRNAs) have been proposed to implicate in resistance to chemotherapeutic drugs. However, whether circNRIP1 is involved in the development of hypoxia-ind...

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Detalles Bibliográficos
Autores principales: Xu, Guangsong, Li, Mingliang, Wu, Jiang, Qin, Chunhong, Tao, Yin, He, Hongjie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7186590/
https://www.ncbi.nlm.nih.gov/pubmed/32425596
http://dx.doi.org/10.2147/CMAR.S246272