Cilostazol, a Phosphodiesterase 3 Inhibitor, Moderately Attenuates Behaviors Depending on Sex in the Ts65Dn Mouse Model of Down Syndrome

People with Down syndrome, which is a trisomy of chromosome 21, exhibit intellectual disability from infancy and neuropathology similar to Alzheimer’s disease, such as amyloid plaques, from an early age. Recently, we showed that cilostazol, a selective inhibitor of phosphodiesterase (PDE) 3, promote...

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Detalles Bibliográficos
Autores principales: Tsuji, Masahiro, Ohshima, Makiko, Yamamoto, Yumi, Saito, Satoshi, Hattori, Yorito, Tanaka, Emi, Taguchi, Akihiko, Ihara, Masafumi, Ogawa, Yuko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7186592/
https://www.ncbi.nlm.nih.gov/pubmed/32372946
http://dx.doi.org/10.3389/fnagi.2020.00106

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7186592/
https://www.ncbi.nlm.nih.gov/pubmed/32372946
http://dx.doi.org/10.3389/fnagi.2020.00106

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