Telomere dysfunction promotes small vessel vasculitis via the LL37-NETs-dependent mechanism

BACKGROUND: Small vessel vasculitis (SVV) is a group of systemic autoimmune diseases that are mediated by neutrophil extracellular traps (NETs) in response to cathelicidin LL37, an aging molecular marker, which could be induced by telomere dysfunction. Therefore, in this study, we evaluated the hypo...

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Detalles Bibliográficos
Autores principales: Lu, Yingying, Jiang, Hong, Li, Bingjue, Cao, Luxi, Shen, Qixia, Yi, Weiwei, Ju, Zhenyu, Chen, Liangliang, Han, Fei, Appelgren, Daniel, Segelmark, Mårten, de Buhr, Nicole, von Köckritz-Blickwede, Maren, Chen, Jianghua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AME Publishing Company 2020
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7186648/
https://www.ncbi.nlm.nih.gov/pubmed/32355801
http://dx.doi.org/10.21037/atm.2020.02.130

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7186648/
https://www.ncbi.nlm.nih.gov/pubmed/32355801
http://dx.doi.org/10.21037/atm.2020.02.130

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