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Telomere dysfunction promotes small vessel vasculitis via the LL37-NETs-dependent mechanism
BACKGROUND: Small vessel vasculitis (SVV) is a group of systemic autoimmune diseases that are mediated by neutrophil extracellular traps (NETs) in response to cathelicidin LL37, an aging molecular marker, which could be induced by telomere dysfunction. Therefore, in this study, we evaluated the hypo...
Autores principales: | Lu, Yingying, Jiang, Hong, Li, Bingjue, Cao, Luxi, Shen, Qixia, Yi, Weiwei, Ju, Zhenyu, Chen, Liangliang, Han, Fei, Appelgren, Daniel, Segelmark, Mårten, de Buhr, Nicole, von Köckritz-Blickwede, Maren, Chen, Jianghua |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
AME Publishing Company
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7186648/ https://www.ncbi.nlm.nih.gov/pubmed/32355801 http://dx.doi.org/10.21037/atm.2020.02.130 |
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