Cornel iridoid glycoside ameliorates cognitive deficits in APP/PS1/tau triple transgenic mice by attenuating amyloid-beta, tau hyperphosphorylation and neurotrophic dysfunction

BACKGROUND: Targeted proteinopathy is involved in creating pharmacological agents that protect against Alzheimer disease (AD). Cornel iridoid glycoside (CIG) is an effective component derived from Cornus officinalis. The present study aimed to determine the effects of CIG on β-amyloid (Aβ) and tau p...

Descripción completa

Detalles Bibliográficos
Autores principales: Yang, Cuicui, Bao, Xunjie, Zhang, Li, Li, Yali, Li, Lin, Zhang, Lan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AME Publishing Company 2020
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7186687/
https://www.ncbi.nlm.nih.gov/pubmed/32355772
http://dx.doi.org/10.21037/atm.2020.02.138

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7186687/
https://www.ncbi.nlm.nih.gov/pubmed/32355772
http://dx.doi.org/10.21037/atm.2020.02.138

Ejemplares similares