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Efficacy and safety of iloprost in patients with septic shock‐induced endotheliopathy—Protocol for the multicenter randomized, placebo‐controlled, blinded, investigator‐initiated trial

BACKGROUND: In Europe 700.000 new cases of sepsis occur annually and more than 100.000 of these patients die due to multiorgan failure (MOF). We have identified shock‐induced endotheliopathy (SHINE) to be associated with development of MOF and mortality. Furthermore, in patients with septic shock th...

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Detalles Bibliográficos
Autores principales: Bestle, Morten H., Clausen, Niels E., Søe‐Jensen, Peter, Kristiansen, Klaus T., Lange, Theis, Johansson, Pär I., Stensballe, Jakob, Perner, Anders
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7186821/
https://www.ncbi.nlm.nih.gov/pubmed/31950481
http://dx.doi.org/10.1111/aas.13546