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Synthetic and Biological Studies on New Urea and Triazole Containing Cystobactamid Derivatives

Cystobactamids belong to the group of arene‐based oligoamides that effectively inhibit bacterial type IIa topoisomerases. Cystobactamid 861‐2 is the most active member of these antibiotics. Most amide bonds present in the cystobactamids link benzoic acids with anilines and it was found that some of...

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Detalles Bibliográficos
Autores principales: Planke, Therese, Cirnski, Katarina, Herrmann, Jennifer, Müller, Rolf, Kirschning, Andreas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7186842/
https://www.ncbi.nlm.nih.gov/pubmed/31834653
http://dx.doi.org/10.1002/chem.201904073