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Structurally unique PARP‐1 inhibitors for the treatment of prostate cancer

The prognosis for metastatic castration‐resistant prostate cancer is unfavorable, and although Poly(ADP)‐ribose polymerase‐1 (PARP‐1) inhibitors have shown efficacy in the treatment of androgen‐receptor dependent malignancies, the limited number of options present obstacles for patients that are not...

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Detalles Bibliográficos
Autores principales: Divan, Ali, Sibi, Mukund P., Tulin, Alexei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7186898/
https://www.ncbi.nlm.nih.gov/pubmed/32342655
http://dx.doi.org/10.1002/prp2.586