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Localized endothelial‐based control of platelet aggregation and coagulation under flow: A proof‐of‐principle vessel‐on‐a‐chip study

BACKGROUND: In the intact vessel wall, endothelial cells form a barrier between the blood and the remaining vascular structures, serving to maintain blood fluidity and preventing platelet activation and fibrin clot formation. The spatiotemporal space of this inhibition is largely unknown. OBJECTIVE:...

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Detalles Bibliográficos
Autores principales: Brouns, Sanne L.N., Provenzale, Isabella, van Geffen, Johanna P., van der Meijden, Paola E.J., Heemskerk, Johan W.M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7187151/
https://www.ncbi.nlm.nih.gov/pubmed/31863548
http://dx.doi.org/10.1111/jth.14719