MicroRNA‐124a inhibits endoderm lineage commitment by targeting Sox17 and Gata6 in mouse embryonic stem cells

The role of microRNAs (miRNAs) during mouse early development, especially in endoderm germ layer formation, is largely unknown. Here, via miRNA profiling during endoderm differentiation, we discovered that miR‐124a negatively regulates endoderm lineage commitment in mouse embryonic stem cells (mESCs...

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Detalles Bibliográficos
Autores principales: Liew, Lee Chuen, Gailhouste, Luc, Tan, Geok Chin, Yamamoto, Yusuke, Takeshita, Fumitaka, Nakagama, Hitoshi, Ochiya, Takahiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Inc. 2019
Materias:
Embryonic Stem Cells/Induced Pluripotent Stem Cells
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7187259/
https://www.ncbi.nlm.nih.gov/pubmed/31828873
http://dx.doi.org/10.1002/stem.3136

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7187259/
https://www.ncbi.nlm.nih.gov/pubmed/31828873
http://dx.doi.org/10.1002/stem.3136

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