Cargando…

Phase 1 Pharmacokinetic Study of AZD5718 in Healthy Volunteers: Effects of Coadministration With Rosuvastatin, Formulation and Food on Oral Bioavailability

AZD5718 is a first‐in‐class small‐molecule anti‐inflammatory drug with the potential to reduce the residual risk of cardiovascular events after myocardial infarction in patients receiving lipid‐lowering statin therapy. Leukotrienes are potent proinflammatory and vasoactive mediators synthesized in l...

Descripción completa

Detalles Bibliográficos
Autores principales: Ericsson, Hans, Nelander, Karin, Heijer, Maria, Kjaer, Magnus, Lindstedt, Eva‐Lotte, Albayaty, Muna, Forte, Pablo, Lagerström‐Fermér, Maria, Skrtic, Stanko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7187334/
https://www.ncbi.nlm.nih.gov/pubmed/31793171
http://dx.doi.org/10.1002/cpdd.756