Cargando…

Isoindoline‐Based Nitroxides as Bioresistant Spin Labels for Protein Labeling through Cysteines and Alkyne‐Bearing Noncanonical Amino Acids

Electron paramagnetic resonance (EPR) spectroscopy in combination with site‐directed spin labeling (SDSL) is a powerful tool in protein structural research. Nitroxides are highly suitable spin labeling reagents, but suffer from limited stability, particularly in the cellular environment. Herein we p...

Descripción completa

Detalles Bibliográficos
Autores principales: Braun, Theresa Sophie, Widder, Pia, Osswald, Uwe, Groß, Lina, Williams, Lara, Schmidt, Moritz, Helmle, Irina, Summerer, Daniel, Drescher, Malte
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7187341/
https://www.ncbi.nlm.nih.gov/pubmed/31657498
http://dx.doi.org/10.1002/cbic.201900537