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The Pharmacokinetics and Relative Bioavailability of Mepolizumab 100 mg Liquid Formulation Administered Subcutaneously to Healthy Participants: A Randomized Trial

This study compared the pharmacokinetic (PK) profile of a new liquid formulation of mepolizumab with the established lyophilized formulation. In this open‐label, parallel‐group, single‐dose study (NCT03014674; GSK ID: 204958), healthy participants were randomized (1:1:1) to receive a single mepolizu...

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Detalles Bibliográficos
Autores principales: Shabbir, Shaila, Pouliquen, Isabelle J., Bentley, Jane H., Bradford, Eric S., C. Kaisermann, Morrys, Albayaty, Muna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7187405/
https://www.ncbi.nlm.nih.gov/pubmed/31317668
http://dx.doi.org/10.1002/cpdd.726