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Histone ChIP‐Seq identifies differential enhancer usage during chondrogenesis as critical for defining cell‐type specificity

Epigenetic mechanisms are known to regulate gene expression during chondrogenesis. In this study, we have characterized the epigenome during the in vitro differentiation of human mesenchymal stem cells (hMSCs) into chondrocytes. Chromatin immunoprecipitation followed by next‐generation sequencing (C...

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Detalles Bibliográficos
Autores principales: Cheung, Kathleen, Barter, Matthew J., Falk, Julia, Proctor, Carole J., Reynard, Louise N., Young, David A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7187454/
https://www.ncbi.nlm.nih.gov/pubmed/32058623
http://dx.doi.org/10.1096/fj.201902061RR