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LncGBP9/miR-34a axis drives macrophages toward a phenotype conducive for spinal cord injury repair via STAT1/STAT6 and SOCS3

BACKGROUND: Acute spinal cord injury (SCI) could cause mainly two types of pathological sequelae, the primary mechanical injury, and the secondary injury. The macrophage in SCI are skewed toward the M1 phenotype that might cause the failure to post-SCI repair. METHODS: SCI model was established in B...

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Detalles Bibliográficos
Autores principales: Zhou, Jiahui, Li, Zhiyue, Wu, Tianding, Zhao, Qun, Zhao, Qiancheng, Cao, Yong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7187522/
https://www.ncbi.nlm.nih.gov/pubmed/32345320
http://dx.doi.org/10.1186/s12974-020-01805-5