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LncGBP9/miR-34a axis drives macrophages toward a phenotype conducive for spinal cord injury repair via STAT1/STAT6 and SOCS3
BACKGROUND: Acute spinal cord injury (SCI) could cause mainly two types of pathological sequelae, the primary mechanical injury, and the secondary injury. The macrophage in SCI are skewed toward the M1 phenotype that might cause the failure to post-SCI repair. METHODS: SCI model was established in B...
Autores principales: | Zhou, Jiahui, Li, Zhiyue, Wu, Tianding, Zhao, Qun, Zhao, Qiancheng, Cao, Yong |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7187522/ https://www.ncbi.nlm.nih.gov/pubmed/32345320 http://dx.doi.org/10.1186/s12974-020-01805-5 |
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