A Single-Dose Combination Study with the Experimental Antimalarials Artefenomel and DSM265 To Determine Safety and Antimalarial Activity against Blood-Stage Plasmodium falciparum in Healthy Volunteers

Artefenomel and DSM265 are two new compounds that have been shown to be well tolerated and effective when administered as monotherapy malaria treatment. This study aimed to determine the safety, pharmacokinetics, and pharmacodynamics of artefenomel and DSM265 administered in combination to healthy s...

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Detalles Bibliográficos
Autores principales: McCarthy, James S., Rückle, Thomas, Elliott, Suzanne L., Ballard, Emma, Collins, Katharine A., Marquart, Louise, Griffin, Paul, Chalon, Stephan, Möhrle, Jörg J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2019
Materias:
Clinical Therapeutics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7187626/
https://www.ncbi.nlm.nih.gov/pubmed/31685476
http://dx.doi.org/10.1128/AAC.01371-19

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7187626/
https://www.ncbi.nlm.nih.gov/pubmed/31685476
http://dx.doi.org/10.1128/AAC.01371-19

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