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Evaluation of Concordance Between Deficient Mismatch Repair and Microsatellite Instability Testing and Their Association with Clinicopathological Features in Colorectal Cancer

BACKGROUND: Microsatellite instability (MSI) is one of the most important molecular characteristics of colorectal cancer (CRC), which mainly results from defective DNA mismatch repair (MMR). This study was performed to investigate the concordance between deficient MMR and MSI testing, and to evaluat...

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Detalles Bibliográficos
Autores principales: Bai, Huili, Wang, Rong, Cheng, Wei, Shen, Yifan, Li, Haijun, Xia, Wei, Ding, Zhenglin, Zhang, Yuhong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7187941/
https://www.ncbi.nlm.nih.gov/pubmed/32425600
http://dx.doi.org/10.2147/CMAR.S248069