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Evocalcet prevents ectopic calcification and parathyroid hyperplasia in rats with secondary hyperparathyroidism

BACKGROUND: Elevated parathyroid hormone (PTH) levels in secondary hyperparathyroidism (SHPT) lead to vascular calcification, which is associated with cardiovascular events and mortality. Increased PTH production is caused by the excessive proliferation of parathyroid gland cells, which is accelerat...

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Detalles Bibliográficos
Autores principales: Sakai, Mariko, Tokunaga, Shin, Kawai, Mika, Murai, Miki, Kobayashi, Misaki, Kitayama, Tetsuya, Saeki, Satoshi, Kawata, Takehisa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7188245/
https://www.ncbi.nlm.nih.gov/pubmed/32343734
http://dx.doi.org/10.1371/journal.pone.0232428