A genome-wide analysis of DNA methylation identifies a novel association signal for Lp(a) concentrations in the LPA promoter

Lipoprotein(a) [Lp(a)] is a major cardiovascular risk factor, which is largely genetically determined by one major gene locus, the LPA gene. Many aspects of the transcriptional regulation of LPA are poorly understood and the role of epigenetics has not been addressed yet. Therefore, we conducted an...

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Detalles Bibliográficos
Autores principales: Coassin, Stefan, Hermann-Kleiter, Natascha, Haun, Margot, Wahl, Simone, Wilson, Rory, Paulweber, Bernhard, Kunze, Sonja, Meitinger, Thomas, Strauch, Konstantin, Peters, Annette, Waldenberger, Melanie, Kronenberg, Florian, Lamina, Claudia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7188291/
https://www.ncbi.nlm.nih.gov/pubmed/32343731
http://dx.doi.org/10.1371/journal.pone.0232073

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7188291/
https://www.ncbi.nlm.nih.gov/pubmed/32343731
http://dx.doi.org/10.1371/journal.pone.0232073

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