Insights into adenosine A(2A) receptor activation through cooperative modulation of agonist and allosteric lipid interactions

The activation process of G protein-coupled receptors (GPCRs) has been extensively studied, both experimentally and computationally. In particular, Molecular Dynamics (MD) simulations have proven useful in exploring GPCR conformational space. The typical behaviour of class A GPCRs, when subjected to...

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Detalles Bibliográficos
Autores principales: Bruzzese, Agustín, Dalton, James A. R., Giraldo, Jesús
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7188303/
https://www.ncbi.nlm.nih.gov/pubmed/32298258
http://dx.doi.org/10.1371/journal.pcbi.1007818

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7188303/
https://www.ncbi.nlm.nih.gov/pubmed/32298258
http://dx.doi.org/10.1371/journal.pcbi.1007818

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