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Insights into adenosine A(2A) receptor activation through cooperative modulation of agonist and allosteric lipid interactions
The activation process of G protein-coupled receptors (GPCRs) has been extensively studied, both experimentally and computationally. In particular, Molecular Dynamics (MD) simulations have proven useful in exploring GPCR conformational space. The typical behaviour of class A GPCRs, when subjected to...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7188303/ https://www.ncbi.nlm.nih.gov/pubmed/32298258 http://dx.doi.org/10.1371/journal.pcbi.1007818 |