C9orf72/ALFA-1 controls TFEB/HLH-30-dependent metabolism through dynamic regulation of Rag GTPases

Nutrient utilization and energy metabolism are critical for the maintenance of cellular homeostasis. A mutation in the C9orf72 gene has been linked to the most common forms of neurodegenerative diseases that include amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD). Here we have...

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Detalles Bibliográficos
Autores principales: Ji, Yon Ju, Ugolino, Janet, Zhang, Tao, Lu, Jiayin, Kim, Dohoon, Wang, Jiou
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7188304/
https://www.ncbi.nlm.nih.gov/pubmed/32282804
http://dx.doi.org/10.1371/journal.pgen.1008738

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7188304/
https://www.ncbi.nlm.nih.gov/pubmed/32282804
http://dx.doi.org/10.1371/journal.pgen.1008738

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