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Assessing the Course of Organ Dysfunction Using Joint Longitudinal and Time-to-Event Modeling in the Vasopressin and Septic Shock Trial

Non-mortality septic shock outcomes (e.g., Sequential Organ Failure Assessment score) are important clinical endpoints in pivotal sepsis trials. However, comparisons of observed longitudinal non-mortality outcomes between study groups can be biased if death is unequal between study groups or is asso...

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Detalles Bibliográficos
Autores principales: Harhay, Michael O., Gasparini, Alessandro, Walkey, Allan J., Weissman, Gary E., Crowther, Michael J., Ratcliffe, Sarah J., Russell, James A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer Health 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7188432/
https://www.ncbi.nlm.nih.gov/pubmed/32426746
http://dx.doi.org/10.1097/CCE.0000000000000104