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Centromere deletion in Cryptococcus deuterogattii leads to neocentromere formation and chromosome fusions

The human fungal pathogen Cryptococcus deuterogattii is RNAi-deficient and lacks active transposons in its genome. C. deuterogattii has regional centromeres that contain only transposon relics. To investigate the impact of centromere loss on the C. deuterogattii genome, either centromere 9 or 10 was...

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Detalles Bibliográficos
Autores principales: Schotanus, Klaas, Heitman, Joseph
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7188483/
https://www.ncbi.nlm.nih.gov/pubmed/32310085
http://dx.doi.org/10.7554/eLife.56026