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Early chromatin shaping predetermines multipotent vagal neural crest into neural, neuronal and mesenchymal lineages
The enteric nervous system (ENS) predominantly originates from vagal neural crest cells (VNC) that emerge from the caudal hindbrain, invade the foregut and populate the gastrointestinal tract. However, the gene regulatory network (GRN) orchestrating the early specification of VNC remains unknown. Us...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7188519/ https://www.ncbi.nlm.nih.gov/pubmed/31792380 http://dx.doi.org/10.1038/s41556-019-0428-9 |