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Antiviral activities of type I interferons to SARS-CoV-2 infection

There is an urgent need to identify antivirals to curtail the COVID-19 pandemic. Herein, we report the sensitivity of SARS-CoV-2 to recombinant human interferons α and β (IFNα/β). Treatment with IFN-α or IFN-β at a concentration of 50 international units (IU) per milliliter reduces viral titers by 3...

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Detalles Bibliográficos
Autores principales: Mantlo, Emily, Bukreyeva, Natalya, Maruyama, Junki, Paessler, Slobodan, Huang, Cheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier B.V. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7188648/
https://www.ncbi.nlm.nih.gov/pubmed/32360182
http://dx.doi.org/10.1016/j.antiviral.2020.104811