Cargando…

Mitochondrial division inhibitor (mdivi-1) decreases oxidative metabolism in cancer

BACKGROUND: Previous studies suggested that mdivi-1 (mitochondrial division inhibitor), a putative inhibitor of dynamin-related protein (DRP1), decreased cancer cell proliferation through inducing mitochondrial fusion and altering oxygen consumption. However, the metabolic reprogramming underlying t...

Descripción completa

Detalles Bibliográficos
Autores principales: Dai, Wenting, Wang, Guan, Chwa, Jason, Oh, Myung Eun, Abeywardana, Tharindumala, Yang, Yanzhong, Wang, Qiong A., Jiang, Lei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7188673/
https://www.ncbi.nlm.nih.gov/pubmed/32147668
http://dx.doi.org/10.1038/s41416-020-0778-x