N-Myc-induced metabolic rewiring creates novel therapeutic vulnerabilities in neuroblastoma

N-Myc is a transcription factor that is aberrantly expressed in many tumor types and is often correlated with poor patient prognosis. Recently, several lines of evidence pointed to the fact that oncogenic activation of Myc family proteins is concomitant with reprogramming of tumor cells to cope with...

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Detalles Bibliográficos
Autores principales: Tjaden, Britta, Baum, Katharina, Marquardt, Viktoria, Simon, Mareike, Trajkovic-Arsic, Marija, Kouril, Theresa, Siebers, Bettina, Lisec, Jan, Siveke, Jens T., Schulte, Johannes H., Benary, Uwe, Remke, Marc, Wolf, Jana, Schramm, Alexander
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7188804/
https://www.ncbi.nlm.nih.gov/pubmed/32346009
http://dx.doi.org/10.1038/s41598-020-64040-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7188804/
https://www.ncbi.nlm.nih.gov/pubmed/32346009
http://dx.doi.org/10.1038/s41598-020-64040-1

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