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N-Myc-induced metabolic rewiring creates novel therapeutic vulnerabilities in neuroblastoma
N-Myc is a transcription factor that is aberrantly expressed in many tumor types and is often correlated with poor patient prognosis. Recently, several lines of evidence pointed to the fact that oncogenic activation of Myc family proteins is concomitant with reprogramming of tumor cells to cope with...
Autores principales: | Tjaden, Britta, Baum, Katharina, Marquardt, Viktoria, Simon, Mareike, Trajkovic-Arsic, Marija, Kouril, Theresa, Siebers, Bettina, Lisec, Jan, Siveke, Jens T., Schulte, Johannes H., Benary, Uwe, Remke, Marc, Wolf, Jana, Schramm, Alexander |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7188804/ https://www.ncbi.nlm.nih.gov/pubmed/32346009 http://dx.doi.org/10.1038/s41598-020-64040-1 |
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