Prolonged Persistence of Chimeric Antigen Receptor (CAR) T Cell in Adoptive Cancer Immunotherapy: Challenges and Ways Forward

CAR T cell qualities, such as persistence and functionality play important roles in determining the outcome of cancer immunotherapy. In spite of full functionality, it has been shown that poor persistence of CAR T cells can limit an effective antitumor immune response. Here, we outline specific stra...

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Detalles Bibliográficos
Autores principales: Jafarzadeh, Leila, Masoumi, Elham, Fallah-Mehrjardi, Keyvan, Mirzaei, Hamid Reza, Hadjati, Jamshid
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7188834/
https://www.ncbi.nlm.nih.gov/pubmed/32391013
http://dx.doi.org/10.3389/fimmu.2020.00702

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7188834/
https://www.ncbi.nlm.nih.gov/pubmed/32391013
http://dx.doi.org/10.3389/fimmu.2020.00702

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