Investigating APOE, APP-Aβ metabolism genes and Alzheimer’s disease GWAS hits in brain small vessel ischemic disease

Alzheimer’s disease and small vessel ischemic disease frequently co-exist in the aging brain. However, pathogenic links between these 2 disorders are yet to be identified. Therefore we used Taqman genotyping, exome and RNA sequencing to investigate Alzheimer’s disease known pathogenic variants and p...

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Detalles Bibliográficos
Autores principales: Blumenau, Sonja, Foddis, Marco, Müller, Susanne, Holtgrewe, Manuel, Bentele, Kajetan, Berchtold, Daniel, Beule, Dieter, Dirnagl, Ulrich, Sassi, Celeste
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7188838/
https://www.ncbi.nlm.nih.gov/pubmed/32345996
http://dx.doi.org/10.1038/s41598-020-63183-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7188838/
https://www.ncbi.nlm.nih.gov/pubmed/32345996
http://dx.doi.org/10.1038/s41598-020-63183-5

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