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The synthetic LPS binding peptide 19-2.5 interferes with clotting and prevents degradation of high molecular weight kininogen in plasma

Sepsis and septic shock are life-threatening conditions and remain an important medical problem, emphasizing the need to identify novel therapeutic approaches. Coagulation dysfunction, hypotension, disturbed microcirculation and multiorgan failure occur frequently. These severe conditions result fro...

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Detalles Bibliográficos
Autores principales: Köhler, Juliane, Ehler, Johannes, Kreikemeyer, Bernd, Bajorath, Rika, Schürholz, Tobias, Oehmcke-Hecht, Sonja
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7188841/
https://www.ncbi.nlm.nih.gov/pubmed/32346013
http://dx.doi.org/10.1038/s41598-020-64155-5