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Desmoplastic small round cell tumor is dependent on the EWS-WT1 transcription factor

Desmoplastic small round cell tumor (DSRCT) is a rare and aggressive soft-tissue malignancy with a poor overall survival and no effective therapeutic options. The tumor is believed to be dependent on the continued activity of the oncogenic EWS-WT1 transcription factor. However, the dependence of the...

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Detalles Bibliográficos
Autores principales: Gedminas, Jenna M., Chasse, Maggie H., McBrairty, Mitchell, Beddows, Ian, Kitchen-Goosen, Susan M., Grohar, Patrick J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7188842/
https://www.ncbi.nlm.nih.gov/pubmed/32345977
http://dx.doi.org/10.1038/s41389-020-0224-1