Cargando…

The CDK inhibitor p57(Kip2) enhances the activity of the transcriptional coactivator FHL2

The eukaryotic cell cycle is negatively regulated by cyclin-dependent kinase inhibitors (CKIs). p57(Kip2) is a member of the Cip/Kip family of CKIs and frequently inactivated by genomic mutations associated with human overgrowth disorders. There is increasing evidence for p57 to control cellular pro...

Descripción completa

Detalles Bibliográficos
Autores principales: Kullmann, Michael Keith, Podmirseg, Silvio Roland, Roilo, Martina, Hengst, Ludger
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7188849/
https://www.ncbi.nlm.nih.gov/pubmed/32346031
http://dx.doi.org/10.1038/s41598-020-62641-4