Serine-dependent redox homeostasis regulates glioblastoma cell survival

BACKGROUND: The amino acid serine is an important substrate for biosynthesis and redox homeostasis. We investigated whether glioblastoma (GBM) cells are dependent on serine for survival under conditions of the tumour microenvironment. METHODS: Serine availability in GBM cells was modulated pharmacol...

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Detalles Bibliográficos
Autores principales: Engel, Anna L., Lorenz, Nadja I., Klann, Kevin, Münch, Christian, Depner, Cornelia, Steinbach, Joachim P., Ronellenfitsch, Michael W., Luger, Anna-Luisa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7188854/
https://www.ncbi.nlm.nih.gov/pubmed/32203214
http://dx.doi.org/10.1038/s41416-020-0794-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7188854/
https://www.ncbi.nlm.nih.gov/pubmed/32203214
http://dx.doi.org/10.1038/s41416-020-0794-x

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