Contribution of common and rare damaging variants in familial forms of bipolar disorder and phenotypic outcome

Genome-wide association studies on bipolar disorders (BD) have revealed an additive polygenic contribution of common single-nucleotide polymorphisms (SNPs). However, these SNPs explain only 25% of the overall genetic variance and suggest a role of rare variants in BD vulnerability. Here, we combined...

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Detalles Bibliográficos
Autores principales: Courtois, Elisa, Schmid, Mark, Wajsbrot, Orly, Barau, Caroline, Le Corvoisier, Philippe, Aouizerate, Bruno, Bellivier, Frank, Belzeaux, Raoul, Dubertret, Caroline, Kahn, Jean-Pierre, Leboyer, Marion, Olie, Emilie, Passerieux, Christine, Polosan, Mircea, Etain, Bruno, Jamain, Stéphane
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7188882/
https://www.ncbi.nlm.nih.gov/pubmed/32345981
http://dx.doi.org/10.1038/s41398-020-0783-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7188882/
https://www.ncbi.nlm.nih.gov/pubmed/32345981
http://dx.doi.org/10.1038/s41398-020-0783-0

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