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ACKR4 Recruits GRK3 Prior to β-Arrestins but Can Scavenge Chemokines in the Absence of β-Arrestins

Chemokines are essential for guiding cell migration. Atypical chemokine receptors (ACKRs) contribute to the cell migration process by binding, internalizing and degrading local chemokines, which enables the formation of confined gradients. ACKRs are heptahelical membrane spanning molecules structura...

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Detalles Bibliográficos
Autores principales: Matti, Christoph, Salnikov, Angela, Artinger, Marc, D'Agostino, Gianluca, Kindinger, Ilona, Uguccioni, Mariagrazia, Thelen, Marcus, Legler, Daniel F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7188906/
https://www.ncbi.nlm.nih.gov/pubmed/32391018
http://dx.doi.org/10.3389/fimmu.2020.00720