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ACKR4 Recruits GRK3 Prior to β-Arrestins but Can Scavenge Chemokines in the Absence of β-Arrestins
Chemokines are essential for guiding cell migration. Atypical chemokine receptors (ACKRs) contribute to the cell migration process by binding, internalizing and degrading local chemokines, which enables the formation of confined gradients. ACKRs are heptahelical membrane spanning molecules structura...
Autores principales: | Matti, Christoph, Salnikov, Angela, Artinger, Marc, D'Agostino, Gianluca, Kindinger, Ilona, Uguccioni, Mariagrazia, Thelen, Marcus, Legler, Daniel F. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7188906/ https://www.ncbi.nlm.nih.gov/pubmed/32391018 http://dx.doi.org/10.3389/fimmu.2020.00720 |
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