Myeloid-Derived Suppressor Cell-Derived Arginase-1 Oppositely Modulates IL-17A and IL-17F Through the ESR/STAT3 Pathway During Colitis in Mice

Myeloid-derived suppressor cells (MDSC) play a crucial role in regulating the intestinal immune response during colitis. We previously revealed an essential role of MDSC in promoting TH17 cell polarization, which was found to be arginase-1 (Arg-1)-dependent; however, the underlying mechanism remains...

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Detalles Bibliográficos
Autores principales: Ma, Zhanchuan, Zhen, Yu, Hu, Cong, Yi, Huanfa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7188946/
https://www.ncbi.nlm.nih.gov/pubmed/32391010
http://dx.doi.org/10.3389/fimmu.2020.00687

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7188946/
https://www.ncbi.nlm.nih.gov/pubmed/32391010
http://dx.doi.org/10.3389/fimmu.2020.00687

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