Cargando…
Myeloid-Derived Suppressor Cell-Derived Arginase-1 Oppositely Modulates IL-17A and IL-17F Through the ESR/STAT3 Pathway During Colitis in Mice
Myeloid-derived suppressor cells (MDSC) play a crucial role in regulating the intestinal immune response during colitis. We previously revealed an essential role of MDSC in promoting TH17 cell polarization, which was found to be arginase-1 (Arg-1)-dependent; however, the underlying mechanism remains...
Autores principales: | Ma, Zhanchuan, Zhen, Yu, Hu, Cong, Yi, Huanfa |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7188946/ https://www.ncbi.nlm.nih.gov/pubmed/32391010 http://dx.doi.org/10.3389/fimmu.2020.00687 |
Ejemplares similares
-
Ablation of IL-17A leads to severe colitis in IL-10-deficient mice: implications of myeloid-derived suppressor cells and NO production
por: Tachibana, Masashi, et al.
Publicado: (2019) -
Regulation of DNA‐PK activity promotes the progression of TNBC via enhancing the immunosuppressive function of myeloid‐derived suppressor cells
por: Han, Jiawen, et al.
Publicado: (2022) -
Arteriosclerosis Derived from Cutaneous Inflammation Is Ameliorated by the Deletion of IL-17A and IL-17F
por: Nakanishi, Takehisa, et al.
Publicado: (2023) -
Myeloid-derived suppressor cell depletion therapy targets IL-17A-expressing mammary carcinomas
por: Dawod, Bassel, et al.
Publicado: (2020) -
Myeloid-Derived Suppressor Cells Promote the Progression of Primary Membranous Nephropathy by Enhancing Th17 Response
por: Li, Huimin, et al.
Publicado: (2020)