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Killer Archaea: Virus-Mediated Antagonism to CRISPR-Immune Populations Results in Emergent Virus-Host Mutualism

Theory, simulation, and experimental evolution demonstrate that diversified CRISPR-Cas immunity to lytic viruses can lead to stochastic virus extinction due to a limited number of susceptible hosts available to each potential new protospacer escape mutation. Under such conditions, theory predicts th...

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Detalles Bibliográficos
Autores principales: DeWerff, Samantha J., Bautista, Maria A., Pauly, Matthew, Zhang, Changyi, Whitaker, Rachel J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7188992/
https://www.ncbi.nlm.nih.gov/pubmed/32345641
http://dx.doi.org/10.1128/mBio.00404-20