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Killer Archaea: Virus-Mediated Antagonism to CRISPR-Immune Populations Results in Emergent Virus-Host Mutualism
Theory, simulation, and experimental evolution demonstrate that diversified CRISPR-Cas immunity to lytic viruses can lead to stochastic virus extinction due to a limited number of susceptible hosts available to each potential new protospacer escape mutation. Under such conditions, theory predicts th...
Autores principales: | DeWerff, Samantha J., Bautista, Maria A., Pauly, Matthew, Zhang, Changyi, Whitaker, Rachel J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Microbiology
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7188992/ https://www.ncbi.nlm.nih.gov/pubmed/32345641 http://dx.doi.org/10.1128/mBio.00404-20 |
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