APOBEC3C Tandem Domain Proteins Create Super Restriction Factors against HIV-1

Humans encode proteins, called restriction factors, that inhibit replication of viruses such as HIV-1. The members of one family of antiviral proteins, apolipoprotein B mRNA-editing enzyme catalytic polypeptide-like 3 (APOBEC3; shortened here to A3), act by deaminating cytidines to uridines during t...

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Detalles Bibliográficos
Autores principales: McDonnell, Mollie M., Crawford, Kate H. D., Dingens, Adam S., Bloom, Jesse D., Emerman, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7188997/
https://www.ncbi.nlm.nih.gov/pubmed/32345636
http://dx.doi.org/10.1128/mBio.00737-20

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7188997/
https://www.ncbi.nlm.nih.gov/pubmed/32345636
http://dx.doi.org/10.1128/mBio.00737-20

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