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Reaction of indoles with aromatic fluoromethyl ketones: an efficient synthesis of trifluoromethyl(indolyl)phenylmethanols using K(2)CO(3)/n-Bu(4)PBr in water
A new, mild and efficient protocol for the synthesis of trifluoromethyl(indolyl)phenylmethanols by the reaction of indoles with a variety of aromatic fluoromethyl ketones in the presence of K(2)CO(3) (15 mol %) and n-Bu(4)PBr (15 mol %) in water. The desired products were obtained in good to excelle...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Beilstein-Institut
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7189012/ https://www.ncbi.nlm.nih.gov/pubmed/32395181 http://dx.doi.org/10.3762/bjoc.16.71 |