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Progressive Loss of Corneal Nerve Fibers and Sensitivity in Rats Modeling Obesity and Type 2 Diabetes Is Reversible with Omega-3 Fatty Acid Intervention: Supporting Cornea Analyses as a Marker for Peripheral Neuropathy and Treatment

PURPOSE: To determine whether cornea nerve fiber density and/or corneal function are valid markers for early detection and treatment of peripheral neuropathy in rats modeling prediabetes and type 2 diabetes. METHODS: High-fat feeding combined without or with low-dose streptozotocin was used to creat...

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Detalles Bibliográficos
Autores principales: Coppey, Lawrence, Davidson, Eric, Shevalye, Hanna, Obrosov, Alexander, Torres, Michael, Yorek, Mark A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7189026/
https://www.ncbi.nlm.nih.gov/pubmed/32425569
http://dx.doi.org/10.2147/DMSO.S247571