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Mechanism of Methylprednisolone‐Induced Primary Cilia Formation Disorder and Autophagy in Osteoblasts

OBJECTIVE: To study the role of primary cilia formation disorder and osteoblasts autophagy in the pathogenesis of steroid‐induced avascular necrosis of the femoral head (SANFH). METHODS: Osteoblasts were isolated from rabbit bones and treated with 1 μM Methylprednisolone for 0, 12, 24, 48, and 72 h....

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Detalles Bibliográficos
Autores principales: Zhao, Zhen‐qun, Liu, Wan‐lin, Guo, Shi‐bing, Bai, Rui, Yan, Jing‐long
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons Australia, Ltd 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7189053/
https://www.ncbi.nlm.nih.gov/pubmed/32064763
http://dx.doi.org/10.1111/os.12630