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Astrocytic Glutamate Transporter 1 (GLT1) Deficiency Reduces Anxiety- and Depression-Like Behaviors in Mice

Glutamatergic dysregulation is known to contribute to altered emotional regulation. Astrocytic glutamate transporter 1 (GLT1) is responsible for the majority of glutamate clearance from synapse. However, the role of astrocytic GLT1 in affective processes such as anxiety- and depression-like behavior...

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Detalles Bibliográficos
Autores principales: Jia, Yun-Fang, Wininger, Katheryn, Ho, Ada Man-Choi, Peyton, Lee, Baker, Matthew, Choi, Doo-Sup
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7189218/
https://www.ncbi.nlm.nih.gov/pubmed/32390810
http://dx.doi.org/10.3389/fnbeh.2020.00057